Dr. Jeffrey Pradeep Raj

Associate Professor (Clinical Pharmacology)

Department of Pharmacology

CURRENT ACADEMIC ROLE & RESPONSIBILITIES

    1)     Teaches undergraduate and post graduate students

    2)     Guides undergraduate and postgraduate research

    3)     Consults for sample size estimation and final biostatistical analysis of student/ faculty research

    4)     Resource person for various workshops and conferences on research methodology, good clinical practice, statistics and recent updates in Clinical Pharmacology & therapeutics

    5)     Editorial Board Member, BMC Pharmacology and Toxicology Journal (2023 Impact Factor: 2.605)

    6)     Associate Editor, European Journal of Medical Research Journal (2023 Impact Factor: 4.2)

SUBJECTS CURRENTLY TEACHING

Subject Semester / Year
Clinical Pharmacology MD, MBBS students

ACADEMIC QUALIFICATIONS

Degree Specialisation Institute Year of passing
AFAMS Clinical Pharmacology National Academy of Medical Sciences, New Delhi 13/11/2022
DM Clinical Pharmacology Seth G S Medical College & King Edward Memorial Hospital, Mumbai 15/09/2021
MD Pharmacology St. Johns Medical College and Hospital, Bengaluru 25/07/2018
MBA Hospital Management Bharathiar University 05/2015
PG Diploma in Biostatistics Biostatistics Madurai Kamraj University 11/2014
PG Diploma in Family Medicine Family Medicine Christian Medical College, Vellore 09/2014
MBBS Christian Medical College, Vellore 28/03/2012

Experience

Institution / Organisation Designation Role Tenure
Kasturba Medical College, Manipal (MAHE-Manipal) Associate Professor (Div. of Clinical Pharmacology) 10.05.2024 - present
Sri Ramachandra Medical College & Research Institute Assistant Professor (Div. of Clinical Pharmacology) 24.07.2023 – 09.05.2024
Seth G.S. Medical College & K.E.M Hospital, Mumbai Assistant Professor (Clinical Pharmacology) 28.09.2021 – 21.07.2023
Seth G.S. Medical College & K.E.M Hospital, Mumbai Senior Resident (D.M. Resident) 27.08.2018 – 26.08.2021
St. John’s Medical College, Bangalore PG demonstrator 20.04.2015 – 19.04.2018
CSI Hospital, Erode Medical Officer 03.04.2013 – 15.04.2015
Christian Medical College, Vellore Intern 01.04.2012 – 31.03.2013

1. Optimising Informed CONsent in clinical trials in low- and middle-income settings: feasibility of an adapted QuinteT Recruitment Intervention (QRI) in India (OrION-I)

Principal investigator: Dr. Sangeetha Paramasivan

Co-investigator: Dr. Jeffrey Pradeep Raj

Funding agencies: UK-MRC National Institute for Health Research

Brief overview: 

Clinical trials (CT) are important for scientists to find treatments for complex health problems.  In India, there have been reports of ethical concerns that people taking part in trials were not aware that they were in them (eg. survivors of the Bhopal gas tragedy were recruited to clinical trials without their consent).  Such Concerns led the Indian Supreme Court to halt CTs briefly in 2013.

We are a diverse group of people involved in conducting or promoting the need for ethical CTs across India and the UK.  We are interested in addressing inadequate informed consent, and finding methods that will help improve it.  Particularly, we would like to explore the adaptability of the QuinteT Recruitment Intervention (QRI), which has been shown to optimize recruitment to CTs while safeguarding informed consent in the UK.

2. Evaluation of Newly Designed Flu-vaccine (ENDFLU)

Principal investigator: Dr. Nithya Gogtay

Co-investigator: Dr. Jeffrey Pradeep Raj

Funding agencies: Department of Biotechnology / European Commission

Brief overview: 

The ENDFLU project is aimed at designing the next generation influenza vaccines that induce broader and longer-lasting protection, including through non-virus-neutralizing (non-VN) antibody and cell-mediated immunity. Harmonised and coordinated Phase I and II clinical trials will be performed.

3. Indo-European Consortium for Next Generation Influenza Vaccine Innovation (INCENTIVE)

Principal investigator:  Dr. Nithya Gogtay

Co-investigator: Dr. Jeffrey Pradeep Raj

Funding agencies: Department of Biotechnology / European Commission

Brief overview:

This includes 4 studies

a)      QIV- 1: Immunogenicity, molecular profiling and safety of a marketed quadrivalent influenza vaccine (FluQuadri) administered by the intramuscular route in elderly participants. [HMSC number: 2021-0018]

b)      QIV- 2: Immunogenicity, molecular profiling and safety of a marketed quadrivalent influenza vaccine (FluQuadri) administered by the intramuscular route in children 3-8 years old. [HMSC number: 2021-0332]

c)      QIV- 3: Immunogenicity, molecular profiling and safety of a marketed quadrivalent influenza vaccine (FluQuadri) administered by the intramuscular route in infants 6-12 months of age. [HMSC number: 2021-0333]

d)      Health Economic Study:  The Health Economic study is envisaged to understand the potential demand of the population for the influenza vaccine, to understand which are the characteristics of the vaccine (e.g., effectiveness or severity of the side effects) that can decrease or increase acceptance of the vaccine by the population to maximize future vaccination coverage. 

AREAS OF INTEREST, EXPERTISE AND RESEARCH

Area of Interest

Clinical Trials/research, Clinical Pharmacology, Therapeutics, Research Methodology, Bioethics, and Biostatistics

Area of Expertise

Clinical Trials/research & Biostatistics

Area of Research

New drug and biologic development – human studies

Professional Affiliations & Contributions

1.     Forum for Ethics Review Committees in India (FERCI) - Life Member

2.     Research Society for studies in diabetes in India (RSSDI) - Life Member

3.     Academy of Family Practitioners of India (AFPI) - Life Member

4.     Indian Medical Association (IMA) - Life Member

5.     Medical Students Association of India (MSAI) - Life Member

Efficacy and safety of AP-Bio®(KalmCold®) in participants with uncomplicated upper respiratory tract viral infection (common cold) - A phase III, double-blind, parallel group, randomized placebo-controlled trial.

Raj JP, Maurya MR, Nair N, Marfatia H, Hadaye R, Gogtay NJ. Efficacy and safety of AP-Bio®(KalmCold®) in participants with uncomplicated upper respiratory tract viral infection (common cold) - A phase III, double-blind, parallel group, randomized placebo-controlled trial. Complement Ther Med. 2023 May;73:102934. 

Safety and Efficacy of Moderately-High Dose Turmacin® (Turmerosaccharide >10% w/w) Supplementation on Joint Discomfort in Healthy Adults - A Pilot Proof-of-Concept Single Arm Study.

Raj JP, Venkatachalam S, S Amaravati R. Safety and Efficacy of Moderately-High Dose Turmacin® (Turmerosaccharide >10% w/w) Supplementation on Joint Discomfort in Healthy Adults - A Pilot Proof-of-Concept Single Arm Study. J Diet Suppl. 2023 Feb 14:1-10. 

Population Pharmacokinetics of Hydroxychloroquine Sulfate in Healthcare Workers, Given for Prophylaxis Against Coronavirus Disease 2019 (COVID-19) in India.

Raj JP, Gogtay NJ, Pandey A, Kakkar AK, Shafiq N, Mekala P, Pingali U, Raju AP, Mallayasamy S, Kshirsagar NA. Population Pharmacokinetics of Hydroxychloroquine Sulfate in Healthcare Workers, Given for Prophylaxis Against Coronavirus Disease 2019 (COVID-19) in India. J Clin Pharmacol. 2022 Nov;62(11):1403-1411. 

Effect of behavioural interveNtion on medication aDherence amOng elderly with Select non-communicable disEases (ENDORSE) – Pilot Randomised Controlled Trial.

Raj JP, Matthew B. Effect of behavioural interveNtion on medication aDherence amOng elderly with Select non-communicable disEases  (ENDORSE) – Pilot Randomised Controlled Trial. Geriatr Gerontol Int 2020; 20: 1079–1084. 

Effect of Turmacin supplementation on joint discomfort and functional outcome among healthy participants - A randomized placebo-controlled trial.

Raj JP, Venkatachalam S, Rahca P, Bhaskaran S, Amaravati RS. Raj JP, Venkatachalam S, Racha P, Bhaskaran S, Amaravati RS. Effect of Turmacin supplementation on joint discomfort and functional outcome among healthy participants - A randomized placebo-controlled trial. Complement Ther Med. 2020 Sep;53:102522

Click below to view the complete list of publications.

Books/ Book Chapter

Raj JP, Amaravati RS. Performance enhancing substances and masking agents (Doping) in sports medicine. In: Rajkumar S Amaravati, Hemanth Kumar Alladu., editors. Injuries around the knee – optimizing clinical outcomes. 1st edition. Wolters Kluwer.