CURRENT ACADEMIC ROLE & RESPONSIBILITIES
Dr Nitesh Kumar is Assistant Professor [Selection Grade] at the Department of Pharmacology, MCOPS Manipal.
Details of his research can be viewed by browsing the following links. https://scholar.google.com/citations?user=1vu3-VoAAAAJ&hl=en
https://www.scopus.com/authid/detail.uri?authorId=25928530900
SUBJECTS CURRENTLY TEACHING
| Subject | Semester / Year |
|---|---|
| Pharmacology 1 | Second year PharmD |
| Pharmacology 2 | Third year PharmD |
| Pharmacology-2 Lab | Third Year PharmD |
| Pharmacology & Toxicology | Second year DPharm |
| Cellular and Molecular Pharmacology | MPharm semester-1 |
| Pharmacology practicals | MPharm semester-1 |
| Pharmacology & Toxicology practical | Second year DPharm |
| Pharmacological and Toxicological Screening Methods-II | Second semester MPharm |
| Pharmacology practical II | Second semester MPharm |
| Research work | Third and fourth semester MPharm |
ACADEMIC QUALIFICATIONS
| Degree | Specialisation | Institute | Year of passing |
|---|---|---|---|
| PhD | Hepatoprotection, anticancer study | Manipal College of Pharmaceutical Sciences | 2013 |
| M Pharm | Pharmacology [Cancer] | Manipal College of Pharmaceutical Sciences | 2008 |
| B Pharm | --- | Manipal College of Pharmaceutical Sciences | 2006 |
Experience
| Institution / Organisation | Designation | Role | Tenure |
|---|---|---|---|
| Department of Pharmacology, MCOPS Manipal | Assistant Professor - Selection Grade | Teaching and Research | 2016 till date |
| Department of Pharmacology, MCOPS Manipal | Assistant Professor- Senior Scale | Teaching and Research | 2014-16 |
| Department of Pharmacology, MCOPS Manipal | Assistant Professor | Teaching and Research | 2013-14 |
| Department of Pharmacology, MCOPS Manipal | Lecturer | Teaching and Research | 2010-12 |
| Department of Pharmacology, MCOPS Manipal | Research Associate | Research in a Ranbaxy sponsored project | 2008-10 |
AREAS OF INTEREST, EXPERTISE AND RESEARCH
Area of Interest
Screening of pharmacological activity the molecules from herbal and synthetic source, Development of nano formulation (Liposomes), Toxicological study of molecules from herbal and synthetic source, Pharmacokinetic study of drugs and formulation
Area of Expertise
Toxicological studies of biomedical and pharmacutical products, In vitro and in vivo screening the molecules for anticancer, neurological, hepato-protective and hypo-lipidaemic activities , Development of Liposomes and phytosomes of herbal drugs, Pharmacokinetic study of drugs and formulation
Area of Research
In vitro and in vivo anticancer activity , Hypolipidaemic screening of herbal drugs, Development of Liposomes and phytosomes of herbal drugs, Hepatoprotective screening of herbal drugs and formulation, Pharmacokinetic study of drugs and formulation
Total number of publications: 59
A few research papers are listed below. For more details, you may kindly browse the following link- https://manipal.pure.elsevier.com/en/persons/k-nitesh
Impact of caffeic acid on aluminium chloride-induced dementia in rats
2013-01-01 Nampoothiri M Krishnadas N Rao C M Mudgal J
Journal of Pharmacy and Pharmacology, 2013.
Preliminary investigation of cytotoxic potential of 2-quinolone derivatives using in vitro and in vivo (solid tumour and liquid tumour) models of cancer
2013-01-01 Jayashree B S Dhamija I Parihar V
Arabian Journal of Chemistry, 2013, Kumar, N, Dhamija, I, Raj, PV, Jayashree, BS, Parihar, V, Manjula, SN, Thomas, S, Kutty, NG, Rao C M.
An appraisal of cinnamyl sulfonamide hydroxamate derivatives (HDAC inhibitors) for anti-cancer, anti-angiogenic and anti-metastatic activities in human cancer cells
Reddy ND Shoja MH Biswas S Nayak PG Kumar N Rao CM
Chemico-biological interactions. 2016 25;253:112-24.
Preliminary evaluation of in vitro cytotoxicity and in vivo antitumor activity of Premna herbacea Roxb. in Ehrlich ascites carcinoma model and Dalton's lymphoma ascites model
2013-01-01 Parihar V Manjula SN Dhamija I
Experimental Toxicologic and Pathology, 2013.
Toxicological evaluation of Terminalia paniculata bark extract and its protective effect against CCl4-induced liver injury in rodents
2013-01-01 K Nandakumar Bansal P Shenoy RR
BMC Complementary and alternative medicine, 2013.
High carbohydrate diet with 30% sucrose solution: an optimised rodent model for simulating human insulin resistance
2013-01-01 Shenoy RR Mudgal J Rao M C
Pharmacologia, 2013.
Elucidation of structure-activity relationship of 2-quinolone derivatives and exploration of their antitumor potential through bax-induced apoptotic pathway
2012-01-01 Rao CM Raj VP Jayshree VP
Chemical Biology and Drug Design, 2012.
Synthesis and evaluation of selected 1, 3, 4-oxadiazole derivatives for in vitro cytotoxicity and in vivo anti-tumor activity
Tiwari A Kutty NG Kumar N Chaudhary A Raj PV Shenoy RR Rao CM
Cytotechnology.2016:1-15. (In Press)
Evaluation of Ceiba pentandra (L.) Gaertner bark extracts for in vitro cytotoxicity on cancer cells and in vivo antitumor activity in solid and liquid tumor models
Kumar R Kumar N Ramalingayya GV Setty MM Pai KSR
Cytotechnology.2016:1-13 (In Press)
Preliminary investigation of cytotoxic potential of 2-quinolone derivatives using in vitro and in vivo (solid tumor and liquid tumor) models of cancer
Kumar, N Dhamija, I Raj, P.V Jayashree, B.S Parihar, V Manjula, S.N Thomas, S Kutty, N.G Rao C. M
Arab. J. Chem. 2014;7(4): 409–417.
Silymarin liposomes improves oral bioavailability of silybin besides targeting hepatocytes, and immune cells
Kumar, N Rai A Reddy, N.D Raj P.V. Jain, P Deshpande, P Mathew, G Kutty, N.G Udupa, N Rao, C.M
Pharmacol. Rep. 2014; 66(5):788–798.
Insulin blocks glutamate-induced neurotoxicity in differentiated SH-SY5Y neuronal cells
Nampoothiri, M Reddy, N.D John, J. Kumar, N Kutty, Nampurath. G Rao, Chamallamudi. M
Behavioural Neurology. 2014 (2014), 1-8.
Atypical antidepressant activity of 3,4-bis(3,4-dimethoxyphenyl)furan-2,5-dione isolated from heart wood of Cedrus deodara, in rodents
Kumar, N Dhayabaran, D Nampoothiri, M Nandakumar, K. Puratchikody, A Lalani, N Dawood, K Ghosh, A
Korean. J. Physiol. Pharmacol. 2014; 18(5):365-369
Hepatoprotective role of caesalpenia bonduc: A histopathological and biochemical study
Sumalatha, S Pai, K.S Kumar, N Bhat, K.M
J Clin Diagn Res. 2014;8(11):HF05-7.
In vitro and in vivo Hepatoprotective Action of L-α-phosphatidylcholine in Alcohol-induced Toxicity Model
Raj PV Mudgal J Reddy ND Rao CM Bansal P Rai A Kumar N
International Journal of Pharmaceutical Sciences Review and Research, 2016;41(1): 171-176
In vivo evaluation of two thiazolidin-4-one derivatives in high sucrose diet fed pre-diabetic mice and their modulatory effect on AMPK, Akt and p38 MAP kinase in L6 cells
J Mudgal P Shetty Nayak PG Kumar N Kishore A Kutty NG Nandakumar K Shenoy RR Rao CM Joseph A et al
Frontiers in Pharmacology. 2016;7:381
Oral Administration of Decitabine Nanoparticles Effectively Suppresses Nmu - Induced Leukaemia in Sprague - Dawley Rats and Arrests K562 Cells in S - Phase
P Jain M Tiwari N Kumar A Chonkar JV Rao N Udupa
International Journal of Pharmaceutical and Clinical Research 8 (8), 1260 – 1268
Evaluation of Ceiba pentandra (L.) Gaertner bark extracts for in vitro cytotoxicity on cancer cells and in vivo antitumor activity in solid and liquid tumor models
Kumar R Kumar N Ramalingayya GV Setty MM Pai KSR
Cytotechnology. 2016;68(5):1909-23
Synthesis and evaluation of selected 1, 3, 4-oxadiazole derivatives for in vitro cytotoxicity and in vivo anti-tumor activity
Tiwari A Kutty NG Kumar N Chaudhary A Raj PV Shenoy RR Rao CM
Cytotechnology. 2016;68(6):2553-2565
Standardised extract of safed musli (Chlorophytum borivilianum) increases aphrodisiac potential besides being safe in male Wistar rats
Das S Singhal S Kumar N Rao CM Sumalatha S Dave J Dave R Nandakumar K
Andrologia. 2016;48(10):1236-1243
Bioequivalence study of fixed dose combination of enalapril 20mg and lercanadipine 10mg tablet in healthy human volunteers under fasting condition.
2014-01-08 Dave Sunny Kamlesh [MPharm]
The project was conducted in clinical research department of Torrent Research Centre, Bhat, Gandhi Nagar, Gujarat. The pivotal study involved assessment of bioequivalence of fixed dose combination of enalapril maleate 20 mg and lercanadipine 10mg tablet on healthy human volunteers under fasting.
Chemopreventive activity of methanolic extract of Saraca asoca bark against doxorubicin-induced toxicity
2015-03-08 Sri Pragnya Cheruku [MPharm]
We have standardized the methanolic extract of Saraca asoca bark using catechin and epicatechin as marker. The standardized extract was evaluated for chemoprotection against doxorubicin in in vitro using IMR-32 Neuroblastoma cell line and in vivo in rat [2014-2015]