Dr Alex Joseph
Professor
Date of Joining: 08.04.2004
Department of Pharmaceutical Chemistry
CURRENT ACADEMIC ROLE & RESPONSIBILITIES
- Approved PhD Guide, guiding PhD students for their Doctoral Degree
- Research Coordinator for Department of Pharmaceutical Chemistry
- Taking theory and practical classes for BPharm & MPharm students
- Guiding PG students (2nd MPharm) for their research projects
Dr. Alex Joseph is Professor in the Department of Pharmaceutical Chemistry at MCOPS.
He is
SUBJECTS CURRENTLY TEACHING
| Subject | Semester / Year |
|---|---|
| Medicinal Chemistry-I | Fourth Semester BPharm |
| Medicinal Chemistry-II | Fifth Semester BPharm |
| Pharmaceutical Validation | First Semester MPharm (Pharmaceutical Analysis) |
| Food Analysis | First Semester MPharm (Pharmaceutical Analysis) |
| Pharmaceutical Analysis Practical-I | First Year MPharm |
| Modern Bioanalytical Techniques | Second Semester MPharm |
| Pharmaceutical Process Chemistry | Second Semester MPharm |
| Molecular Modelling & Drug Design (Elective) | Third Semester MPharm |
ACADEMIC QUALIFICATIONS
| Degree | Specialisation | Institute | Year of passing |
|---|---|---|---|
| PhD | Pharmaceutical Chemistry/Analysis | Manipal Academy of Higher Education | 2009 |
| M.Pharm | Pharmaceutical Chemistry | Periyar College of Pharmaceutical Sciences, Chennai | 2000 |
Experience
| Institution / Organisation | Designation | Role | Tenure |
|---|---|---|---|
| Department of Pharmaceutical Chemistry, MCOPS | Associate Professor | 2011-till date | |
| Department of Pharmaceutical Chemistry, MCOPS | Assistant Professor | 2009-2011 | |
| Department of Pharmaceutical Chemistry, MCOPS | Senior Lecturer | 2007-2009 | |
| Department of Pharmaceutical Chemistry, MCOPS | Lecturer | 2004-2007 | |
| Sri Guru Ram Rai Institute of Technology and Science, College of Pharmaceutical Sciences, Deharadun, Uttaranchal | Lecturer | 2001-2004 | |
| College of Pharmaceutical Sciences, Mahatma Gandhi University, Cheruvandoor, Ettumanoor, Kerala | Guest Lecturer | 2000-2001 |
AREAS OF INTEREST, EXPERTISE AND RESEARCH
Area of Interest
Teaching Pharmaceutical Organic & Medicinal Chemistry, Research in the Area of Drug design, Drug Discovery and Development, Analytical Research & Development
Area of Expertise
Synthesis of heterocyclic organic compounds, Handling of drug design and molecular docking software like V-Life Sciences Molecular Design Suite, Autodock etc, Handling of advanced analytical instruments like U.V spectrophotometer, IR spectrometer, HPLC, GC-MS, LC-MS etc
Area of Research
Drug design, Synthetic Organic and Medicinal Chemistry, Phytochemical Investigation of Plant extracts, Chemical Modifications of Compounds Isolated from Natural Sources, In vitro and In vivo evaluation of compounds/ extracts for Anticancer, Anti-inflammatory, Antibacterial and Immunomodulatory activities, Analytical Research & Development
Professional Affiliations & Contributions
- Received Best Teacher Award of MCOPS for four times, in the year 2012-13 and 2014-2015, 2016-17, and 2018-19 respectively
- Prof. M.L. Khorana Memorial Best Paper Award for year 2007- Best paper
award in the field of Pharmaceutical analysis and Bioanalytical chemistry
published in IJPS 69(4) 540-545 during the year 2007
- Life member of Association of Pharmaceutical Teachers of India (APTI).
- Life member of Kerala State Pharmacy Council.
In vitro and In vivo Anticancer Activity of Semisynthetic Derivatives of Betulinic acid
2019 Alex Joseph, K K. Srinivasan, Nampurath G. Kutty, Sudheer Moorkoth, Angel T. Alex, Naseer Maliyakkal
Latin American Journal of Pharmacy 38 (8), 1582-90, 2019 (Impact Factor: 0.4)
Neuromodulatory potential of phenylpropanoids; para-methoxycinnamic acid and ethyl-p-methoxycinnamate on aluminum-induced memory deficit in rats.
2019 Samita Rijal, Nilanjan Changdar, Manas Kinra, Ayush Kumar, Madhavan Nampoothiri, Devinder Arora, Rekha R. Shenoy, , K. Sreedhara Ranganath Pai
Toxicology Mechanisms and Methods 29(5), 334-343, 2019 (Impact Factor: 1.994)
Design, Synthesis and Biological Evaluation of Oxindole-Based Chalcones as Small-Molecule Inhibitors of Melanogenic Tyrosinase
2017 Sharad Kumar Suthar, Sumit Bansal, Niteen Narkhede, Manju Guleria, Angel Treasa Alex, Alex Joseph
Chemical and Pharmaceutical Bulletin 65, 833–839, 2017 (Impact factor: 1.445)
In vivo Evaluation of Two Thiazolidin-4-one Derivatives in High Sucrose Diet Fed Pre-diabetic Mice and Their Modulatory Effect on AMPK, Akt and p38 MAP Kinase in L6 Cells
2016 Jayesh Mudgal, Shetty P, Netheen Reddy Akhila HS, Gourishetti K, Mathew G, Alex Joseph
Frontiers in Pharmacology 7, 381, 2016 (Impact factor: 3.845)
Design, synthesis, and biological evaluation of oxindole derivatives as antidepressive agents.
2015 Sharad Kumar Suthar, Sumit Bansal, Md. Maqusood Alam, Varun Jaiswal, Amit Tiwari, Anil Chaudhary, Angel Treasa Alex, Alex Joseph
Bioorganic& Medicinal Chemistry Letters 25, 5281–5285, 2015 (Impact factor: 2.5)
1-Triacontanol cerotate; isolated from Marsilea quadrifolia Linn. ameliorates reactive oxidative damage in the frontal cortex and hippocampus of chronic epileptic rats.
2015 Snehunsu A, Chitrini G, Mamta K, Yadav Pramod K, Nayak BS, Raghavendra Rao K, Alex Joseph
Journal of Ethnopharmacology 172, 80-84, 2015 (Impact factor: 3.608)
Development and evaluation of carboplatin-loaded PCL nanoparticles for intranasal delivery.
2016 Alex AT, . Alex Joseph, Shavi G, Rao JV, Udupa N
Drug Delivery 23(7), 2144-2153, 2016 (Impact factor: 4.845)
Design and synthesis of novel 2-phenyl-5-(1,3-diphenyl-1H-pyrazol-4-yl)-1,3,4-oxadiazoles as selective COX-2 inhibitors with potent anti-inflammatory activity.
2014 Sumit Bansal, Manju Bala, Sharad Kumar Suthar, Shivani Choudhary, Shoumyo Bhattacharya, Varun Bhardwaj, Sumit Singla, Alex Joseph
European Journal of Medicinal Chemistry 80, 167-174, 2014 (Impact factor: 5.552)
Synthesis, in vitro anticancer and antioxidant activity of thiadiazole substituted thiazolidin-4-ones
2013 Alex joseph, Chaitanyakumar Shah, Suthar sharad kumar, Angel treasa alex, Naseer maliyakkal, Sudheer moorkoth, Jessy elizabeth mathew
Acta Pharm 63, 397–408, 2013 (Impact factor: 1.588)
Novel quinolone substituted thiazolidin-4-ones as anti-inflammatory,anticancer agents: Design, synthesis and biological screening
2013 Sharad Kumar Suthar, Varun Jaiswal, Sandeep Lohan, Sumit Bansal, Anil Chaudhary, Amit Tiwari, Angel Treasa Alex, Alex Joesph
European Journal of Medicinal Chemistry 63, 589-602, 2013 (Impact factor: 5.552)
Analytical Method Development and Validation by HPLC & HPTLC, Preformulation Studies and Dissolution Method Development
2006-01-01 Tarunveer Singh
(PG), 2006.
Method development and validation for the estimation of related substances in tadalafil and assay of tadalafil by RP-HPLC
2007-01-01 Prithi Jain
(PG), 2007.
Synthesis of compounds as kinase inhibitor
2007-01-01 Mukul Lakhani
(PG), 2007.
Synthesis of Imidazolone and Quinazolinones derivatives as anticancer agents
2008-01-01 Aravind Pai
2008.
Synthesis and biological activity of thiazolidin-2-ones and indolin-2-ones
2009-01-01 Chithanya Shah
(PG), 2009.
Synthesis and biologicak evaluation of Quinolone substituted thiazolidinones and 3-substituted indolin-2-ones
2010-01-01 Sharad Kumar
(PG), 2010.
Synthesis and Biological evaluation of Quinolone substituted Quinazolinones and Imidazolones
2011-01-01 Santosh Kumar
(PG), 2011.
Novel benzopyrone substituted Thiazolidin-4-ones: synthesis and biological evaluation
2012-01-01 Rimjim Kumari
(PG), 2012.
Novel thiazole substituted thaiazolidinones: synthesis and biological screening
Jignesh Aghara
PG (2013-2014)
Synthesis and Biological evaluation of Thiazole Substituted Schiff bases and thiazolidin-4-ones
Manisha Singh
PG (2014-2015)