Dr S Jyothi Prasanna

Professor & Dean

Manipal Institute of Regenerative Medicine


    Dr.S Jyothi Prasanna is Professor in the Manipal Institute of Regenerative Medicine.

    She is:

    • Group Head of Adult Stem Cell Group.
    • Coordinator for MPhil in Regenerative Medicine. 
    • Academic Coordinator for Indo-SriLankan joint programme for MSc in Stem Cells and Regenerative Medicine.




Subject Semester / Year
Mechanisms of stem cell renewal First Semester
Translation First Semester
Transplantation First Semester
Stem cell niches Second Semester
Liver morphogenesis Second Semester
Endoderm differentiation Second Semester
Stem cells in tumorogenisis Third Semester
Allogeneic stem cell transplantation Third Semester
Homing of stem cells Third Semester


Degree Specialisation Institute Year of passing
PhD Biochemistry IISC, Bengaluru 2005
MPhil Biotechnology JNU, Delhi 1998


Institution / Organisation Designation Role Tenure
Manipal Institute of Regenerative Medicine, Bangalore Associate Professor 2011-Present
School of Regenerative Medicine, Bangalore Group head, Adult Stem cell Group Teaching and training MSC, Diploma, MPhil and PhD students 2007-Present
School of Regenerative Medicine, Bengaluru Assistant Professor 2007-2011
Stem Cell Research Centre, Manipal Hospital Research Scientist Setting up the allogeneic clinical trials with human MSCs. Training and teaching JRFs and SRFs immunoassays relevant for setting up in vitro platforms to validate immuno-modulatory potential of allogeneic MSCs 2006-2007

Comparative analysis of adult stem cells from different tissues reflects differences in cell surface profiles, plasticity and immuno-modulatory potential

2007-01-01 Divya Gopalakrishnan Satish Totey

Presentation at International Society for Stem Cell Research (ISSCR), Cairns, Australia .

Immuno-modulation by human bone marrow derived mesenchymal stem cells upon priming with pro-inflammatory cytokines

2009-01-01 Divya Gopalakrishnan BV Anoop Shilpa Rani

Presentation at International Society for Stem Cell Research (ISSCR), Barcelona.

Hierarchical organisation of cancer stem like cells (cscs) in human hepatocellular carcinomas (hcc): insights into the molecular machinery prevalent in csc like sub-populations

2010-01-01 Parvathy Venugopal Shilpa Rani Shankar BV Anoop

Presentation at International Society for Stem Cell Research (ISSCR) 8th Annual meeting , San Francisco, USA .

Mesenchymal stem cells from Bone marrow and Umbilical cord stroma as cellular and immune therapeutics: does the source matter?


National Conference on Medical Biotechnology and Clinical Research held at IISc, Bangalore.

Mesenchymal Stem cells as cellular immune-modulators


CME at Department of Biochemistry, KIMS (Kampegowda Institute of Medical Sciences), Bangalore.


Area of Interest

Hepatobiology, Trans-differentiation, Transplantation Immunology, Basic mechanisms of stem cell renewal and differentiation, Hormonal influences on stem cells and aging

Area of Expertise

Immunology, Hepatobiology, Stem cell biology

Area of Research

Elucidating the role of stem cells in injury resolution and repair, Factors influencing differentiation of embryonic and adult stem cells to endoderm derivatives, Hormonal elements in connective tissue differentiation-implications in obesity and osteoporosis

Professional Affiliations & Contributions

  • Member of the Society of Biological chemists.
  • Member of the International Society for Stem Cell Research (ISSCR).
  • Editorial Board Member of International Journal of Stem Cell Research and Transplantation (IJST). 
  • Advisor of Stempeutics Research Pvt Limited.

Wharton’s Jelly Mesenchymal stem cells as off-the-shelf cellular therapeutics: A closer look into their regenerative and immune-modulatory propertiesm

2011-01-01 V Soumya Jahnavi

The Open Tissue Engineering and Regenerative Medicine Journal .

Pro-inflammatory cytokines, IFNgamma and TNFalpha, influence immune properties of human bone marrow and Wharton jelly mesenchymal stem cells differentially

Gopalakrishnan D Shankar SR Vasandan AB

2010, PLoS On, 5(2):e9016 .

Gene modulation and immune-regulatory roles of IFNgamma Cytokine

2009-01-01 Banishree Saha Bhagawat Chndrashekar Nandi D

Involvement of oxidative and nitrosative stress in modulation of gene expression and functional responses by IFN gamma in a hepatoma cell line

2007-01-01 Saha B Nandi D

2007, Int. Immunol., Vol 19(7), Pg 867-79.

The MHC-encoded class I molecule, H-2Kk, demonstrates distinct requirements of assembly factors for cell surface expression: roles of TAP, Tapasin and beta2-microglobulin

2004-01-01 Nandi D

Molecular Immunology, Elsevier, Vol 41, Pg 1029-45 .

Differential requirements for optimal cell surface expression of MHC class I molecules

2003-01-01 Nandi D

H-2Kk and H2-Dd 10th Proceedings of Asian Oceanian Biochemists and Molecular Biologists, Pg 152-160 .

5 Functional differences in mesenchymal stromal cells from human dental pulp and periodontal ligament

2013-01-01 Anoop Babu Vasandan Shilpa Rani Shankar Priya Prasad V Sowmya Jahnavi

Journal of Cellular and Molecular Medicine .

Master Adult Stem Cells from Corneal Tissue


Patent No 1588 / CHE / 2006

Characterisation of Cancer stem cells from Hepatoblastomas

2010-01-01 Divya N

PG Student from Mahatama Gandhi University, Changancherry, Kerala.

Isolation and characterisation of human periodontal ligament derived stem cells

2009-01-01 Dr Deepa Ponniyan

MD student of Manipal College of Dental Sciences, Manipal University.

Comparison of stem cells isolated from human dental pulp and human exfoliated deciduous teeth

2007-01-01 Dr Vinay Rao

MD student of Dayanandsagar Instistute of Dental Sciences, Bangalore.

Tumour cell lines as model systems to evaluate the role of stem cell like cells in carcinogenesis

2009-01-01 Parvathy Venugopal

MSc student SORM, Manipal University.

Influence of 17-β Estradiol on cell survival and Differentiation potential of BMMSCs

2011-01-01 Joshua Keppen

MPhil student, SORM, Manipal University.

Characterisation and Mesenchymal stem cell properties of stromal cells isolated from Dental pulp and periodontal ligament

2012-01-01 Dr Manjunath N M

MPhil, SORM, Manipal University.

Effect of negative regulators of signalling on differentiation of Mesenchymal stem cells

2009-01-01 Sheetal Mary Sunny

MSc student Vellore Institute of Technology, Vellore University.