Dr Kamalesh D Mumbrekar
Associate Professor
Department of Radiation Biology and Toxicology
CURRENT ACADEMIC ROLE & RESPONSIBILITIES
- Teaches theory/practical to BSc, MSc, PG diploma students
- Guides students (BSc/ MSc) in their project work
- Undertake research projects and guide PhD student
- Class In-charge MSc Medical Biotechnology
- Participates in institutional activities like workshops, science day, inspire program, refresher course etc.
- Radiation Safety Officer (RSO-1)
- QMR and Single point of contact for Quality’
Kamalesh D Mumbrekar is Associate Professor in the Department of Radiation Biology & Toxicology at Manipal School of Life Sciences.
He:
SUBJECTS CURRENTLY TEACHING
| Subject | Semester / Year |
|---|---|
| Biology-1 (Theory) | BSc, I Semester |
| Biology-1 (Practical) | BSc, I Semester |
| Cell Biology-1 (Theory) | BSc, II Semester |
| Cell Biology-1 (Practical) | BSc, II Semester |
| Basics of Biotechnology (Theory) | BSc Biotechnology, I Semester |
| Molecular Biology (Practical) | BSc, III Semester |
| Project BSc | BSc, VI Semester |
| Project MSc | MSc, IV Semester |
| Radiobiology | First Year BSc MRT |
| Radiobiology | First Year MSc MRP |
ACADEMIC QUALIFICATIONS
| Degree | Specialisation | Institute | Year of passing |
|---|---|---|---|
| PhD | Radiation Biology (Cellular and Molecular Analysis of Normal Tissue Toxicity Induced by Radiotherapy In Breast Cancer Patients) | Department of Radion Biology & Toxicology, School of Life Sciences, Manipal University, Manipal | 2015 |
| MPhil | Zoology | Annamalai University, Tamil Nadu | 2011 |
Experience
| Institution / Organisation | Designation | Role | Tenure |
|---|---|---|---|
| Manipal School of Life Sciences | Associate Professor | 1 April 2022 to till date | |
| Division of Radiobiology & Toxicology, School of Life Sciences | Assistant Professor | October 2015 to 30 March 2022 | |
| Division of Radiobiology & Toxicology, School of Life Sciences | Lecturer | 2008 - 2015 | |
| Division of Radiobiology & Toxicology, School of Life Sciences | Senior Research Fellow | 2007 - 2008 |
• Low dose radiation effects on Brain
• Gut-brain axis in pelvic radiation induced neurological alterations
• Microgravity induced changes in gut microbiota and brain
• Gut dysbiosis and cancer progression and treatment response
• Synthetic lethality in colon cancer
AREAS OF INTEREST, EXPERTISE AND RESEARCH
Area of Interest
Radiation biology, Toxicology
Area of Expertise
Cellular and molecular Radiobiology, DNA repair, Cellular and molecular Neurotoxicology
Area of Research
Low-dose radiation effects, Non-targeted radiation effects through the gut-brain axis, Space radiation biology, Radiation protection, Biodosimetry
Professional Affiliations & Contributions
- Life member of Indian Society for Radiation Biologists, India.
- Life member of Society for Radiation Research, India.
- Life member of Environmental Mutagen Society of India.
- Life member Indian Association for Radiation Protection.
Full Publications List
List of Students project
POST GRADUATE THESIS
2024
- Impact of Ionizing Radiation on DNA Methylation in the Brain Tissue of Mice
- Unveiling the Effects of Pelvic Irradiation on Apoptosis and Mitochondrial Integrity in the Brain via the Gut-Brain Axis
- Exploring the Mechanism of Gut Dysbiosis Induced Neuroinflammation
- Evaluating the Neuroprotective Potential of Taurine on Rotenone-induced Invitro Parkinson’s Disease Model
- Developing Spectroscopic Techniques to Classify the Radiation Exposed Samples for Radiation Biodosimetry Application
- Exploring the brain metabolomic changes in response to pesticide and its link with neurodegenerative diseases
2018
- Effect of Probiotic Treatment on Radiation-Induced Gut Damage in Mouse Model
- Titanium Dioxide Nanoparticle Induced Histological and Biochemical Changes in Mouse Model
2016
- Influence of SNPs in Genes Involved in DNA Repair Pathways on the Radiotherapy Induced Acute Skin Toxicity
2014
- Role of Single Nucleotide Polymorphism in Breast Cancer Predisposition
2012
- Genetic polymorphisms and its role in radiotherapy induced acute skin reactions
2011
- Visualization and Counting of Damage-spots in Lymphocyte Nuclei from Fluorescence-Microscope-images
- Cellular and Molecular Evaluation of Normal Tissue Acute Skin Reaction Induced by Radiotherapy
2009
- 2D Fluorescent Image Analysis for Automation Approach to Quantifying DNA Damages using γ-H2AX
UNDERGRADUATE THESIS SUPERVISED
2024
- Effect of radiation on genes involved in neurodegenerative diseases and DNA repair in Brain Tissue
- Effect of low dose Malathion exposure on DNA Methylation related genes in Mice Brain
- Three-dimensional bioprinted tissue-engineered dermal construct for toxicological studies
- Impact of Microgravity on Genotoxicity of DNA Damaging Agents
- Mitigation of Radiation-Induced Gastrointestinal Damage and Inflammation Using Bacterial Supplementation
- Does pelvic radiation induce changes in neuronal cell maturation in the dentate gyrus region of a rat model?
- Neuroinflammatory potential of organophosphate pesticides (malathion) in mouse
- Understanding the mechanism of genotoxicity induced by Malathion in glial cells
- The Effect of Antibiotics on the Gut-Brain Axis in rat model
- Investigating The Effects of Malathion on Mitochondria in Neuroglial Cells
- Understanding the Effect of Environmental Neurotoxicants on the Genes Involved in Neuronal Survival and Plasticity
- To Understand the effect of Pesticides on Brain Metabolites in Mouse Model
2019
- Mitigation of Cisplatin Induced Cognitive Impairments by Naringenin
- Role of Naringinin in Mitigating the Cisplatin Induced Organ Toxicity in Mouse Model
2018
- Titanium Dioxide Nanoparticle Exposure and Structural Changes in the Hippocampal Neuron -Preclinical Study