The division of Radiobiology and Toxicology undertakes both teaching (Biotechnology, Biomedical engineering, Bachelors and Masters in Nuclear Medicine Technology, Medical Physics, MD Radiotherapy) and interdisciplinary research activities with the goal of developing a comprehensive translational research program for integrating basic science research with clinical implications. The multi-disciplinary research programmes of the division include experimental oncology, molecular radiobiology, genetic toxicology, DNA damage and repair, radiation biodosimetry, radio-sesensitisation and radioprotection and environmental toxicology. Considering the importance of genetic basis for radiobiological phenomenon and cellular response, the conventional radiobiological research questions are also addressed with the molecular tools. Over the years the divisional research activities have been supported by various government funding agencies such as ICMR, CSIR, DAE, DRDO, UGC, AERB and DBT in addition to private funding agencies. The division is also undertaking national and international collaborative research projects. With its excellent credentials in the field of cytogenetics, the department has been accredited the status of Biodosimetry Centre by Atomic Energy Regulatory Board (AERB), Dept. of Atomic Energy, Govt. of India. This is one among the three centers chosen by AERB in India.
Vision
Understanding biological response to ionising radiation and environmental toxicants at the molecular, cellular and physiological level, and to extend this knowledge for designing new strategies for the treatment of cancer and to protect normal cells from xenobiotic induced toxicities.
Training courses offered:
- Tissue culture module
- Genetic toxicology module
- Biochemical analysis module
- Anticancer drug screening module (animal tumour maintenance both in vitro & in vivo)
- Laboratory mice breeding and maintenance.
Laboratory tests offered:
Toxicology tests: Cytotoxicity (MTT assay) & Clonogenic assay
Cytogenetic tests: Micronucleus assay, Comet assay, H2AX foci assay for DNA double strand break analysis
Contact address:
Head of the Department
Radiobiology and Toxicology
Manipal Life Sciences Centre
Manipal University,
Manipal – 576 104
Email: radiobiology.mlsc@manipal.edu