Molecular biology laboratory:
Facilities necessary for all molecular biology related work is available in four separate laboratories. Laboratory with routine instrumentations such as PCRs, Gel doc systems, western blots, electrophoresis units etc.
Mammalian cell culture laboratory:
There are half a dozen fully equipped with microscopes (including fluorescence) in tissue culture laboratories available for research, diagnostic and teaching purposes.
Microarray laboratory:
Agilent microarray 2 micron scanner with bioanalyser and hybridisation ovens to undertake microarray array analysis for high throughput gene expression, epigenetics and SNP analysis.
DNA Sequencing laboratory:
DNA sequencer ABI, 3130 Genetic Analyser with 16 capillaries for sequence and fragment analysis purposes.
Flow Cytometry laboratory:
Flow cytometer (BD FACS Calibur) is available for Teaching, Research and Diagnostic purposes.
Mass Spectrometry laboratory:
MS-QTOF with HPLC for proteomics analysis.
Imaging laboratory:
Fluorescent scanner and high resolution image capture microscopy.
Microbiology laboratory:
State of the art microbiology laboratory.
Atomic Absorption spectrometry laboratory:
For elemental analysis of clinical, environmental and biological samples are available.
HPLC Laboratory:
Three separate HPLC machines with the detectors such as UV, visible, fluorescence, electrochemical and PD are available.
Radioisotope laboratory:
Separate radioactive material handling facility with liquid scintillation counters, scanners etc. are available.
Biophysics laboratory:
The Biophysics laboratory conducts experiments on biological/ pre-clinical/ clinical samples applying Laser Induced Fluorescence and Photoacoustic Spectroscopy to evaluate their spectral information related to diseased and non-diseased conditions. Experiments of Low Level Laser Therapy (LLLT) for tissue regeneration are also conducted in this laboratory.
Common Instrumentation laboratory:
It consists of large scale bacterial incubator/ shaker, high speed and ultra high speed centrifuges, frozen and paraffin block preparation microtomes.
Tissue culture facility:
Well equipped tissue culture room for the maintenance of human normal and tumour cell lines, mouse tumour cells lines, repository and for experimentation.
Animal house facility:
The centralised, state - of the – art, air conditioned animal house with separate breeding, experimentation and sterilization rooms with relevant instrumentations. The facility mainly houses mice of various strains (Balb/c, Swiss albino and C57BL6) as well as rats.
Animal tumour facility:
Routine transplantable tumour maintenance for experimentation in the form of both solid (fibrosarcoma and melanoma), ascities form (Ehrlich, P388, Daltons lymphoma etc.) and nude mouse facility for growing xenograft tumours.
Irradiation facilities:
In-house: Faxitron CP160 X-ray machine and Neutron source
Genetic toxicology and Analytical facility:
With fluorescence (Olympus, Carl Zeiss) & light microscopes and image analysis systems, spectrophotometers (Shimadzu) for routine biochemical and cytotoxicity assays
Bioinformatics lab:
Well equipped Computers with Linux/Windows Operating System, and Sun Server system for data analysis (including microarray data) with a good storage capacity.
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Computer Lab: Computers inbuilt with Linux (Ubuntu, CentOS) and Windows operating systems are dedicated for student purposes.
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Cluster facility: To analyse bulk data generated from the genomic, proteomic platforms and to host in-house bioinformatics tools bioinformatics department has a cluster of SunFire X4100 servers.
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Manipal Computational Biology Interface (MCBI): Bioinformatics department has developed an in-house tool which connects Life Science content management system (LS-CMS), Local Blast programs, Post Epigenomic Analysis Pipeline and Mass spectrometry search engines etc to analyse data locally. We use Python, Java, C++ as tool development programming and R, MatLab as statistical programming language.
Plant Biotechnology lab:
Well equipped culture room for the plant cell, tissue and organ culture for different experiments.
Green House facility:
MLSC has state of the art independent green house of 40×80 feet in size for plant hardening of in vitro raised plantlets and for further experiments. Green house also has 100 important medicinal plants for research purpose.